Analysing the Bioactive Compound of Earthworm Pheretima Javanica Extract by Using Gas Chromatography Mass Spectrum

Abstract

Research Based Learning (RBL) is a learning method that uses contextual
learning, authentic learning, problem solving, cooperative learning, hands on and
minds on learning and inquiry learning. The STEM approach in learning is
expected to provide meaning to students through the systematic integration of
research-based knowledge, concepts and skills. STEM design begin with the
identification of social problems. The social issue of typhoid fever cases caused by
Salmonella enterica Typhi bacteria with a high mortality rate in the world is a
public health problem. The existence of Pheretima javanica which is abundant in
the environment can be utilized by conducting antibacterial activity testing and
analysis of bioactive compounds by students on the form of the extract. This
research is a development research carried out with the aim of developing a
product and also a qualitative descriptive research which serves to provide an
overview of the object. The steps in carrying out these tests were identified as part
of learning that hone creative thinking skills. The results of the class experimental
research showed that the N-Gain score was 0.8, which is in the high category.
These results show that the application of developing problem-based learning tools
with a STEM approach is effective. Learning outcomes contribute to the effort to
find alternative drugs that are effective and do not cause resistance. In addition,
students also produce scientific articles as learning products. This paper has
implications for STEM integrated research-based learning.